Diphenhydramine Hydrochloride Injection, USP is a sterile, pyrogen-free antihistamine solution for intravenous (IV) or intramuscular (IM) administration. This injection is effective in treating various conditions, including allergic reactions, motion sickness, and parkinsonism when oral administration is impractical.
Key Benefits:
- Allergic Reaction Relief: Provides fast-acting relief for allergic reactions to blood products or plasma and acts as an adjunct in anaphylaxis after acute symptoms are controlled.
- Motion Sickness Treatment: Useful for the active management of motion sickness in situations where oral intake is restricted.
- Antiparkinsonism Support: Assists in managing mild cases of parkinsonism, particularly for elderly patients or those intolerant to stronger agents.
Dosage and Administration:
For Intravenous or Intramuscular Use Only:
- Adults: 10 to 50 mg IV at a rate not exceeding 25 mg/min, or deep IM. Maximum daily dosage is 400 mg.
- Pediatric Patients: 5 mg/kg/24 hr or 150 mg/m²/24 hr, divided into four doses. Maximum daily dosage is 300 mg. Adjust dosage based on patient needs and response, and inspect visually for particulate matter or discoloration before administration.
Why Choose Diphenhydramine Hydrochloride Injection?
- Rapid Onset for Emergency Situations: Quick-acting antihistamine relief for emergency or critical care settings.
- Multiple Clinical Applications: Trusted in various conditions, including allergic reactions, motion sickness, and parkinsonism management.
- Available in Convenient Single-Dose Vials: Supplied as 50 mg/mL in single-dose vials for controlled, accurate dosing.
Warnings:
- Use with Caution in the Elderly: Increased risk of sedation, dizziness, and hypotension; monitor closely.
- Avoid in Neonates and Premature Infants: Contraindicated in neonates and infants due to increased sensitivity.
- Avoid Subcutaneous Administration: Subcutaneous or intradermal use may cause local necrosis.
Disclaimer:
This product description was generated by AI and is intended for informational purposes only. Please consult the latest package insert.
