Magnesium Sulfate Injection, USP is a sterile, concentrated solution designed for intravenous (IV) or intramuscular (IM) use. This prescription-only injection is an effective electrolyte replenisher, commonly used to manage magnesium deficiencies and prevent seizures in eclampsia.
Key Benefits:
- Electrolyte Replenishment: Quickly restores magnesium levels in patients suffering from acute magnesium deficiency, preventing related symptoms like muscle irritability and tremors.
- Anticonvulsant Properties: Controls seizures in pre-eclampsia and eclampsia by inhibiting neuromuscular transmission.
- Sterile and Safe: Manufactured to the highest safety standards, ensuring a nonpyrogenic, preservative-free solution for clinical use.
Dosage and Administration:
This solution must be diluted before intravenous use. Dosage depends on the patient’s condition:
- Magnesium Deficiency: 1 gram (2 mL) injected IM every 6 hours for 4 doses, or 5 grams added to 1 liter of 5% Dextrose Injection for slow IV infusion.
- Severe Deficiency: Up to 250 mg/kg of body weight IM within 4 hours.
- Pre-eclampsia/Eclampsia: Initial doses range from 4 to 5 grams IV with additional doses administered as needed to control seizures.
Why Choose Magnesium Sulfate Injection?
- Immediate Action: IV administration offers rapid onset for managing convulsions, while IM doses last up to 4 hours.
- Essential in Critical Care: Widely trusted in clinical settings to manage electrolyte imbalances and prevent life-threatening convulsions in pregnant patients.
Warnings:
- Fetal Harm: Prolonged use in pregnant women can lead to fetal abnormalities, including skeletal demineralization. Not recommended for use beyond 5 to 7 days.
- Renal Caution: Use with caution in patients with impaired kidney function. Monitoring of serum magnesium levels and urine output is essential.
- Incompatible with Certain Solutions: Mixing with solutions containing heavy metals, phosphates, or barium may cause precipitates.
Disclaimer:
This product description was generated by AI and is intended for informational purposes only. Please consult the latest package insert.