Ondansetron Injection, USP is a sterile, nonpyrogenic solution for intravenous (IV) or intramuscular (IM) use, designed to prevent nausea and vomiting associated with emetogenic cancer chemotherapy and postoperative nausea and vomiting. Ondansetron is a selective 5-HT3 receptor antagonist, providing effective antiemetic relief.
Key Benefits:
- Prevention of Nausea and Vomiting: Effective against chemotherapy-induced nausea and postoperative nausea and vomiting, making it essential in oncology and surgical care.
- Multiple Administration Routes: Administered via IV or IM, providing flexibility based on patient needs and clinical setting.
- Clinically Tested: Approved since 1991, widely trusted in oncology and post-surgical care.
Dosage and Administration:
For Intravenous or Intramuscular Use with dilution recommended in specific cases:
- Chemotherapy-Induced Nausea and Vomiting (Adults and Pediatric Patients 6 Months+): 0.15 mg/kg per dose, administered as three doses over 15 minutes, beginning 30 minutes prior to chemotherapy and continuing 4 and 8 hours after the first dose.
- Postoperative Nausea and Vomiting (Adults and Pediatric Patients 1 Month+): Recommended single dose is 4 mg IV or IM, with administration prior to anesthesia or postoperatively if symptoms occur.
Why Choose Ondansetron Injection?
- Proven Antiemetic Effectiveness: Effective in managing nausea and vomiting linked to chemotherapy and surgeries.
- Flexible Dosing and Compatibility: Available in 4 mg/2 mL single-dose vials, designed to accommodate diverse patient needs.
- Safe and Sterile: Supplied as a clear, colorless solution, manufactured under stringent conditions to meet safety standards.
Warnings:
- QT Prolongation and Torsade de Pointes: Can prolong QT interval; monitor patients with risk factors for arrhythmias.
- Serotonin Syndrome Risk: Increased risk when used with other serotonergic drugs.
- Hypersensitivity Reactions: Anaphylactic reactions may occur in patients with previous 5-HT3 antagonist sensitivity.
Disclaimer:
This product description was generated by AI and is intended for informational purposes only. Please consult the latest package insert.
